I recently had AA RTW desk do a re-issue on an ex-CPT AONE6-- a complete and total re-route (I had only used 1 segment, CPT-LHR) and I even changed it from an east-bounder to a west-bounder. Ticket was originally issued by a TA.

The AA RTW desk did a SPECTACULAR job for me-- the aagent I dealt with was so knowledgeable, so friendly, so professional, so helpful and so thorough that by the time I got to the AA CTO in Manhattan it took them less than 5 minutes to print out the entire ticket and collect my $75 + $5 (that's what took the most time!) I was amazed how quickly the ticket spit out after I gave them the locator-- it was instantaneous practically.

Now I did do one thing that made it so easy-- I limited this particular re-issue to 16 flight coupons, so it will have to be re-issued at least one more time, since I'm entitled to many more.

In any case this AA RTW agent has helped other people here and I would be happy to give you her name via e-mail (I don't know if it's best to name her here? Just being ultra-cautious.) But you will find dealing with her to be a delight.