I'm somewhere between "light" and "it depends" because it depends on the reason for the trip. I do some work with a cruise line and if my trip includes a ship visit that can be a couple of weeks long, then I am usually doing public appearances. That means I need to bring along some "show" clothes. BUT, there are marvelous lightweight knits that look great with glittery bling, and once I'm offstage, I depend on stuff I can pack light and wash as needed. (TravelSmith or Orvis are great finds.)
Also end up needing makeup, but there are some marvelous small kits that don't take up much room at all and I can do my TV makeup when onboard the ship.
Other business trips are shorter and I can usually do those with a backpack and a small rollaboard. The longer trips usually require a checked bag slightly bigger than a legal rollaboard. Just gotta depend on washables and knits.
I agree about the whole "why bring the lotions, etc." discussion. Then again, I"m a big "travel size" fan for anything, and that keeps me from having to dash out early in the trip to get stuff. But, later on, yeah -- that's why there are drug stores and chemists in each port.