Just to post an update - more changes have just happened - this time for flights in two weeks time.
These are not just minor schedule changes - they involve complete change of day of operation changes, new routings and new stopovers en-route to the US.
I would advise everyone to check as I find that AA RTW don't get told about these unless they go in a look - no message from LanChile are send to the ticket issuer apparently.