I have asked before on this and got an outright No. Only possibility is if the ticket has not yet been issued (which with business ones I tend to do as close to the time I actually travel as possible).

However if the ticket is already issued and with the state of affairs at the moment I would ask the carrier on the first segment if they would allow this. Recent experience I've had asking for an exemption to some of the other rules (because of forced changes in travel plans) are: AA - quite flexible, BA - fairly inflexible, QF very inflexible.

If anyone has recent experience with the other carriers on granting exemptions to some of the rules I'd be interested to know.

Best of luck.