AA's RTW desk told me a few times that once the itineary is sent to the fare desk and is authorized by the fare desk, that itinerary and the fare computed is valid for 24 hours. If it is not ticketed, it will expire and has to go through the entire process of approval by the fare desk. (And within this time span, if there is a fare increase, it will be recalculated and get a 'new' price.)

The AA agents I talked to told me about this so I had my travel agent issue within that time limit.