I'm planning my next 1w rtw and called the AA rtw desk to check the 3 or 4 continent fares ex BUD, in F and was given 5246 and 5723 respectively. Checked ex FRA and the fares were lower 4965 and 5457 respectively.
Hope this helps someone other than me.
Also keep in mind that travelers in Canada and the U.S. can have those fares issued in their home countries! You still have to originate the itin. in FRA or BUD.