Last year (November) my husband and I went RTW on the mad 100,000 bonus run and bought the tickets originating in Canada. We did it through Amex and we were charged the Canadian rate and the tickets were delivered to us here in the US. I can't find Mark's card (he's the Amex agent) but you can find him on the Amex site under RTW specialists. He's based in Texas and is very knowledgable about RTW as he specialized in this for Amex in their business travel dept.
I'll take a look around for the card. I'm sure I have it someplace. I am the original packrat when it comes to that sort of thing. Hope this helps.
Chris