28" pitch?!? Wow...just mark the whole plane red and include a note to book a bus trip instead.
I've always gone window if possible on long-haul flights. (If I get window I do make sure to board with an empty bladder.

) Failing that, middle-aisle is a no-brainer, regardless of the configuration.
I haven't been on a sold out 2-5-2 in quite some time - that would certainly cause me to rethink middle-aisle. I seem to get a lot of 767 long-hauls.