Hmm... I don't necessarily think an In-N-Out burger is BETTER than other burgers that are twice or three times the price. But for a $2-$3 burger that you can order in a drive-thru, nothing else can even come close.
In any case, I've carried dozens of In-N-Out burgers from LAS to ORD. Order the burgers with the buns on the side. It's definitely not as great as fresh, but still good...and better than anything else remotely close to being called "fast food" in the Chicagoland area.