Lenovo T400 w/8GB RAM and a "home built" i7-930 based desktop w/12GB, both running Win7 64bit. No obvious problems that I could link to any of the updates.

I was having an odd problem where my HP PhotoSmart Premium (C309a) would become unresponsive -- front panel buttons wouldn't do anything; had to power it off and back on again -- if I tried to print to it from the laptop while connected to my work VPN. An updated driver from HP apparently fixed that since it hasn't happened for a couple of weeks now.