Would it be worth the miles/points if I charge $25K for my child's tuition on a CC if the fee is 2.99%?

My first instinct is NO WAY, but on the other hand, I will be paying if off when the statement is due so it's not the interest just the upfront fee I'll have to pay.

Will it be worth it for the AMEX points? The CO Flex EQMs? The BA 2-for-1?

Any thoughts would be greatly appreciated. TIA.