Most of the time I am renting (cheap) B-Class cars for two or three days, so every program that does not take under consideration the amount of money I spent, fits for me. I am choosing Qualiflyer (eg LX, AA, CX) for crediting my car rentals (500 bonus miles per rental).
You need 15.0000 miles for receiving a 600g "gold box" of assorted pralines from Swiss famous Sprüngli or for one bouquet flowers from Fleurop-Interflora delivered as a surprise to whomever you like. With 50 rentals (= 25.000 bonus miles) you are earning a one way upgrade from Y to C on LX from North America to Europe or vv.