We have stayed at Mission Hills and Harborside. Both are great experience in their own way. If you are going with kids harborside a must. Not only is the property awesome you get to use all the facilities at Atlantis-out of this world property which boast of the largest marine habitat. They have a kids club in the evening that allows for the grown ups to have some time for themselves too

Mission Hills is great too but in a desert kind of way. Very enjoyable pool area built with family in mind. The villa's themselves are a 10-in true Westin type fashion. The golf (so I'm told) is great and you of course have access to Westin Mission Hills resort right next door. Plenty to do outside of the property as well not to mention some fine eating-might I recommend the Falls in Palm Springs!
Hopes that helps!