Originally Posted by
efincomputer
Unfortunately there didn't appear to be any flights from SFO to LAS on AA - only LAX to LAS. Would have loved to go via SFO, but draw the line at TWO internal flights each was to get to LAS

.
Definitely fly direct. Messing around with US international and domestic security and immigration is not an enjoyable game.
I've just come back from LAS and we had to get a connecting Virgin America flight (which was admittedly pretty amusing) from SFO on the way out.