Sepulveda has no bike lane in Culver City and cars move a lot faster so safety becomes an issue. You also have to deal with the underpass to 405 freeway. But it is shorter distance wise and probably only suitable for people who are fearless about negotiating the same traffic lane as crazy drivers.
Lincoln has bike lane from the creek to Manchester. And Westchester Parkway has practically no traffic. It's a safer route for bicyclists of moderate ability.