My parents also prefer the window/aisle pairs, when we travel as a family we get 2 window/aisle pairs and a single window seat. We have 2JK,3JK and 4K held for our flight to the Caribbean next July. On the 4-class 777, I would recommend 10AB/JK, as these seem to be some of the quietest seats in the cabin and are close to the exit door so you are among the first to get off.

From what I have heard about 15AB/JK, they are good seats but are quite far down the plane and are adjacent to the WT+ bassinets, which could mean a crying baby will be near! Personally, I do not find the misaligned windows to be that much of a problem. I think 10AB/JK are a very good choice!