General rule for me is that as soon as I sit down I set my watch to destination time and then do whatever it is that I am supposed to be doing. So if flt leaves at 3pm EST (3am HKG) take a few hour nap...and then stay awake till you land.
I firmly believe in the medicated approach to travel. Generally a few glasses of wine at 3pm and Xanex will knock you out for a cpl of hrs (ie the nap) or Halcion and a few classes of wine for the long overnights. The advice about not eating anything heavy is a good one. Even when flying J/F I bring some of my own snacks or a nice salad from the airport b/c the really heavy food will just sit in your stomach and make you generally miserable.