I've used both and I like the regular optical ones more. I guess it is an individual preference. I do a fair about of spreadsheet work as well as VPN/Remote Desktop work...... no gaming. 90% of the surfaces I use the mouse on work just fine.... otherwise I just use it on a piece of paper.

Take a look at this for more info.

http://www.wisegeek.com/what-is-the-...aser-mouse.htm