You probably know that you can book at the airline's website, or even Orbitz/Kayak/whatever using the multi-city function. What you may not realize is that it matters (at least for AA.com) what you choose as the time of departure for each flight segment. For example, on AA.com I wanted the flight departing at 3:30pm, but it would not come up until I chose "Evening" from the drop-down menu. Even "Early evening" didn't give me that particular flight and "Anytime" is not an option. What a pain!

Quoted: "Okay, so you have found multi segments on itasoftware.com. That's great. But, where do you go to book the ticket and get it at the price you find it in ita? I have had the hardest time in figuring that portion out."