I tried it for a one-way rental in France. It was quite happy to take airport codes, but unfortunately I'd like to pick up the car somewhere near central Paris and return it in Bayeux. (Hertz, at least, has offices in both places.) It won't let me enter a non-airport address outside the U.S. and Canada. Is an enhancement for this in the works?
(That said, I liked what I saw for the trial searches I did.)