Hello, I'm brand new! I have lurked before though

Forgive me if this has been addressed before. I tried a search but didn't find exact answers.
I am about to become a very frequent flyer on JetBlue due to my spouse starting a job in Tampa

I am trying to book weekend flights now, but am not sure how early I will be able to get off work on Fridays. I am booking the later flight, although I think 80% of the time I would be able to make the flight before that (late morning).
My questions are:
- do I have to list standby IN PERSON at the airport, or can I call it in? If I make the earlier flight, it would be by a small margin.
- if I can call in, but then I don't make it to the gate in time, what happens? In other words, is there a penalty for listing standby and not showing up to collect standby tickets? Or do I just go back on my normal, booked flight, no harm done?
- any other advice for standby flights?
Thank you very much!