The HR is fairly well commented on, so I'll comment on the Grand Hyatt (nee the Hyatt on Union Square). The hotel (somewhere around 38 stories tall, if memory serves) was built in the mid-1970s on the site of the historic Plaza Hotel and the El Padrino Room restaurant. I stayed a number of times in the first two decades after its opening, but not recently, so I can't offer opinions on the current physical state of the property. There are some very nice views from many rooms on the upper floors.

Its main asset, as the original name attests, is its location facing the northeast corner of Union Square. If a major focus of the weekend is shopping, the location works very well. The Chinatown Gate is just a few short blocks away, and access to the cable car lines is just a block away.

If driving, parking is expensive. If in-and-out access to the car is NOT the city-owned Sutter-Stockton Garage is diagonally across the street from the hotel.