I'm generally in the fly before drive camp, but with our last move to Duluth, MN - 2-1/2 hours from MSP and a great National corporate one-way rate, I'm doing more one-way RTs using the rental cars these days. It has been very convenient to just grab and go, then drop and run, and not consider that my car is sitting in long term. It also generally runs less for the company in mileage reimbursement for personal vehicle use and park, sleep, and fly hotel costs.
--- Coincidentally, I'm posting this from MCO, where our return puts us into MSP for another one-way rental back home.