bigred21,
Maybe you could post the airport(s) from which you typically depart, and the more common routes you might fly in a year. For some people here, the airline in their area and their travel pattern pretty much dictates the choice of airline alliance. In my case, coming out of MSP, DL is my only choice. People living in areas served by several major carriers, and flying lots of different places, may well choose to have several different alliances.
Unless you do an extreme amount of traveling, it generally works better to pick one airline alliance and concentrate your traveling with them. It of course doesn't hurt to be signed up for the others, just to pick up little dribble of miles. But you want to really understand things like which airlines are grouped together, and which fare codes get or don't get miles. If you post a little more about your travel, somebody familiar with that pattern will be able to help you more.
Take note of the Help menu above for decoding the abbreviations on this site. Both the airport code and the glossary.
Romelle