MUT86....where are flying from?.....where do you think you will go?.....how many times/calendar year?.....coach or 1st?...
if your travels can be mostly on 1 carrier, will you be able to reach top tier?...if so, that would be the way to go.....if 2 carriers are convenient for you, then perhaps trying for status on both would make sense....
you should consider things like challenges for status, status matches, upgrades, and premium seating.....
so, if you would post your best guess re my ?'s, you will probably get some specific suggestions.....good luck...