Ditto with Palms or Hard Rock.
You could also throw in Planet Hollywood, as they have a new tower, and the location is ideal.
A lot of these places have some good deals if you sniff around and see what they have - check to see if there are any perks "free upgrades" or "free entry to nightclubs" or "free gambling money/buffet tickets/show tickets/etc."
Caesars just closed the Pussycat Lounge, so your options are already starting to dwindle there.

However, as I mention on my website, it is kind of silly to spend a lot of money for a room when you are almost never going to be in the room except to sleep it off/crash. Seriously, do you think you are going to spend any time in the room other than when you are too tired to stand up? It's not like you guys want to come to Vegas to watch re-runs of Friends on television.

Go for the best price on The Strip, wherever it may be, and just plan on taking taxis to the nightclubs.