That Aeroexpress train runs every 1/2 hour and takes just under an hour. I did waste a little time stumbling about under jet-lag trying to find just how to get rubles and buy the ticket. It looks like it might be possible to buy tickets on-line ahead of time?? The trains are really nice though. Possibly the nicest airport trains I've seen.
At the Belorussky station, the transition from the airport train to the metro was well marked with big black footprints painted on the walkway.
Buying the metro tickets again took me a little while as it is pretty wild there and I was very unsure (and still jet-lagged).
If you have access to Russian currency, maybe you could mail her the necessary rubles so it would save her the money changing step. There were a lot of different machines there and it took me a while to figure out just which ones were the ATMs, and then how to use them. I don't know whether the Aeroexpress would have accepted a credit card.
When one is down in the metro lower level, the signs are only in the Cyrillic script so she will have to know the Red Square stop in that format. Before she plunges down in there she needs to know what she is doing. One of the travel guides - Insight I think - has really good pictures of just how the metro signage looks.
And when I got there, I was sort of awe-struck and ended up forgetting just how I'd walked from the metro. Since I was staying in Moscow for a week it wasn't a problem and eventually I found my way back, but with your friend having a plane to catch it would be more difficult. She needs to be really careful keeping track of her routing for doing the reverse.
I think if she has it totally plotted out, maps in hand, and each step worked out, she could do it successfully. Lots of research, and a sound Plan B (you probably can advise her on the feasibility/workability of cabs?).
And I also think it worth the effort.
Romelle