You'll never see a Part 121 Captain with those minima, although they apply to every aircraft, not just regionals. If the 23 year old, 1500 hour, type rated ATP can get somebody to let him/her do it, (s)he is legally entitled to act as Pilot in Command of an A380.

Anyway, as long as people want to do it, they pay and conditions will remain lousy. Luckily, the accident rates aren't bad because the aircraft are far better than they were even a few years ago. Run if you must fly with some of these people in, say, a 727.