I fly out of Portland and Manchester a lot. I perfer Portland for easy parking and no wait at security (Not that Manchester is bad). Also perfer both Jetblue and Airtran over Southwest. I perfer seat assignments over cattle call boarding.
Anyway, I booked the same cities Portland to Orlando for April. It was $79 each way for Airtran or $129 each way for Jetblue. When I go to Wash DC from Portland, I ususaly go Airtran for the price and $49 upgrade to Business class option on the day of the flight. But to Orlando, I decided on Jetblue because of their non stop. If it was not a non stop, then Airtran would have been a no brainer for me. I also perfer internet (on all Airtran flights) over TV (Jetblue).
Airtran is consistantly lower than Jetblue to Orlando (most other cities too). But Jetblue is more comfortable in coach and has the non stop. It really depends on what is important to you.