Good advice on the credit card front: pick which ones could use the credit card opening bonus to get up to a free ticket, and go.

Now, one thing nobody else has said here (but an old timer like me knows well through experience) is that you're looking at this two-dimensionally, friend. TIME is one of your allies with some of the programs, but not all. For example, the WN Rapid Rewards program gives you a strict 24 mo. cutoff to get that 16th credit, and then you forfeit credits. How long do you have to get the last credits? If it's short, well, time's-a-wasting and you need a new business or personal WN Rapid Rewards card NOW.

With programs like American's, you've got a cutoff (18 mos. with no activity, I think..... I never come close), and you can do absolutely brainless stuff in order to keep it alive (buy something from the mileage mall, dining, etc.), and then just allow your youth to atrophy, your hair to get grey, etc., and over time you'll be up to the magic award you wanted. This is like a marathon, if you're smart: put these mini-miles on the shelf and figure out just what aspirational award you want to get to, then develop a plan, execute it, and enjoy the passage of time until you get there.

I've been on this travel point collection scheme for years and years. I'm in every program, and I just keep collecting (all the while making SURE to keep each program alive, even buying points as a last resort), and after this many years I pretty much go wherever I want to go, whenever, and have taken some of the sweetest and most expensive trips (almost) for free. This is the reward for loyalty, business travel (and seriousness) over many years.

Even though it seems like you've got a mishmash of points left over there (I assume you've used all the awards you could, and that's why this mishmash is left), you can get yourself some fairly valuable awards simply by being pragmatic and designing a plan, then executing it. See you on the road, and don't forget you're in this to get value out of the travel you're already paying for!