I have stayed in a couple of areas and I see nil tourist difference between them as I love to walk and view. The metro/bus system is cheap, fast and really widespread. I always travel to/from the airport on it for 5% of a taxi and it is usually faster than a taxi. Best to buy a 1 day or 5 day or whatever pass. The pass is good on the metro, the bus and possible some trains............
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MisterNice