+1.
Beautiful with wonderful service.

As you have gotten some great ideas for round the world locations; am going to recommend some closer to home and less well known. Most would be better for long weekends - we are rarely able to do a full week, so have gotten to be experts on secondary cities!

Ren Aruba (NOT the Marina, the Suites) - although nice, the hotel may not be particularly "spectacular" - but the the private island that "comes" with it IS -especially the spa at the end of the jetty! Depending on when you choose to go an oceanfront suite may be an option as a Plat upgrade. Aruba loves tourists and treats them very well. Lots of great restaurants within walking distance. Car not needed. Could split with the Marriott if you wanted a full week. Completely different experience between the 2.

Ren Pittsburgh - especially if you like baseball. We consistently receive corner K that overlooks the stadium - surreal to watch the game out the window while listening to the play by play on TV. A wonderful staff.
FallingWater not too far. Some nice museums. A very good microbewery/restaurant in an old church. An underated city.

Ren Austin - again, not spectacular -smack in the center of a shopping center! but the staff makes up for location! Fun city w/ good outlying areas/small towns for a day trip or 2. We enjoyed our stay here far more than we would have expected.

Wentworth by the Sea (New Hampshire) - historic hotel with great restoration. Lots to see and do in the area. Could tie in with Boston, Newport, or Providence RI if have that interest and make it a full week trip.