If you're thinking of award tickets.....

All those points are worth somewhat less than you might believe. The AMEX rewards are in most respects "fare-dollar-based", i.e. 130,000 points will buy you about $1300 worth of ticket, a long, long way from a 1C RT to Europe.

AS miles? I don't know about AS partners (I haven't looked), but an AA 1C RT to Europe averages about 125,000 miles for just one of the "Plan Way Ahead and Hope" variety.... I can recall getting 2 DL Business Elite RTs for 120,000, but that was a while back and hard to do. My last pair were 170,000 for the two, selected over a year ago for a trip in May, '09.

Don't scoff at Business Class vs. FC. For those used to air travel in the US, Business TATL on US legacies is still a "Giant leap ahead".