Hi. I'm not going to get into how to optimize your mileage collections, there are plenty of people here who know far more than I about that.

I do, on average, three AONE4s annually. A quick glance at your initial itinerary shows limited F cabin availability. If you can adjust the itinerary for more CX, BA and new cabin JL F, then I'd say yes, go for the AONE4. QF has a perfectly good F service, but the hard product is lacking, with absolutely no privacy on the 744. I'd say that CX (from experience) and new JL (from what I've read in FT) F cabins are currently the top of OW F.

The lounges by themselves are not worth the extra money, IMO. If you end up traveling on a DONEx, you may very well find someone on FT who will guest you into one or more of the F lounges.