I did a search and couldn't find anything specific on this.

My wife and I want to travel to ORD-TPE in business class in April, 2010. The RT from ORD is very expensive. Around $6,000. We can travel the following one way tickets for half the price. ORD-SFO in coach. SFO-TPE in Z and TPE-ORD in Z.

Are there any disadvantages to booking the trip this way.