As far as I know, there isn't any evidence that "better" hotels have fewer bed bugs. Every time you read a published article on the subject, they're eager to tell you how someone who stayed in a fancy hotel got bedbugs. I dunno. I stay in whatever -- tents, hostels, dumps, fleabags...and all the way to five star suites bigger than my entire house plus garage plus yard with huge multi-player hot tubs overlooking the view. I have not encountered bed bugs. I don't know if there is a genetic component (resistance) or if I've just been lucky. Knock on Wood.

I do not know why sleeping in your clothes or carting around extra sheets would protect you against bed bugs.

I think there is a such a thing as sensitivity to the strong detergents used by some hotel laundries. I bring my own pillow case and I'm fine. If a break out was caused by bed bugs, I don't know why a pillow case would stop them.