Originally Posted by hoteltravelfun

I heard there are some sprays you can use on the bed.

I have been travelling with 2 bed sheets and for the pillow as well. I put these over the hotel made up bed. I take the blanket they give you on the plane. ( I only travel international but not that often). I sometimes take a second blanket as recently I have had an extra seat next to me.
I sleep with heavy athletic socks on my feet.

I may depending on the hotel next time, bring an air matress and sleep on the floor. This may not work for you as you travel.