Thank you all for the great advice. I've been leaning towards the car pick-up and using as a bag storage but it's tricky with my laptop. I can't leave the keys with a valet or garage attendant as a number of employees have had their laptops stolen recently.

For the garage on 5th & Mission, they do not require you to leave your keys? Just want to make sure.

Planning on using most of the transit systems when showing SFO to my fellow co-worker. Golden Gate Ferry so they can see the city, alcatraz, and golden gate bridge from the water, cable car, and then street car. Trying to pack a large amount into one day.