We rented a car for a couple of days in Cappadocia two years ago and had no trouble at all. Yes, it was manual and yes, we got insurance through the car company, but it was a great way of getting around (it was in the summer, so no snow worries).
If you have any experience driving in big cities or outside N. America, I wouldn't hesitate, but what can I say, I'm an NYC driver.
