I don't about going one larger. I have a 5 year old 42" plasma in my family room that doesn't seem too small and don't have any regrets about (well, maybe wishing it had hdmi ports instead of dvi ports). I also have 65" Sharp Aquos (spelling?) LCD for my home theater in the basement and while it looks fine there, I would never want something that big in the family room.

My cousin just moved into a new condo and bought a huge (I'm guessing well over 60") Panasonic Elite. It's way too large for the room, I feel like it's right on your head. Your sitting so close that the picture looks horrible, and plus just looks really tacky to have something that huge in such a small room.