I highly doubt it. I've seen many NY/NJ/PA/MD cars in SFO, and a couple CA cars here in NY. I've also seen very many AZ and NV plates in SFO, but never one of those here. Likewise, I've seen a handful of NJ cars in ORD, and once in a while a car from IL here. ORD usually has a bunch of cars from elsewhere in the Midwest, but only once have I seen a car from MO, IA, and NE around here.
I was told by the agent it's due to the fact that this is a randomly circulating corporate fleet, so they give out whatever they have, wherever the renter wants it to go. The cars are registered in the state where they were first pressed into service, but Hertz Corporation owns all of them. No car "needs" to return "home," and most likely never will be.