In all my life I have never used drugs except an asprin here and there. Now I am traveling to Europe and to Asia and South America 3 or 4 times a year. My Dr prescribed some tablets"Co_Zopiclone 7.5mg. It puts me to sleep for about 5 hours. Absolutely no after affects what so ever. I treally puts one out. I do not drink alcohol on the flight prior to taking it. I always inform my seat mate that will be taking it, just in case. Knocks me out completely. I only use it when flying over night or a flight from Asia, It works for me.