Thanks for all the suggestions guys! I think what we will end up doing is heading to Isla Mujures for the first night, so we can chill and get our bearings and figure out where we want to go from there. I will drop Playa Del Carmen on her and see what she thinks, while keeping in mind that staying in the Zona might be the best call. That sucks that indoor venues are closed, anyone know where to lookup outdoor partying?