I simply want to add from personal experience that Larium (Mefloquine) gave me major psychiatric problems, but in 1992 when I took it, no one knew that it would have an effect on those who suffer from depression. So if you do suffer from depression or take SSRIs, Larium is a definite no-no.

My son is working for an NGO in Ethiopia at present and has been there for 5 months and returns in a month's time. He has to take an antimalarial for a longer course of treatment than many of you holiday makers, and this is the advice from the Tropical Medicine Department at the University Hospital of Mulhouse (France).

Up to a month's stay, Larium.
Up to two months' stay, Malarone
Up to six months stay, Doxycycline.

He is a water engineer and has had to work at the cholera outbreak area of Moyale on the Kenyan/Ethiopian border, and was glad that he's taking Doxycycline because it's the antibiotic of choice to treat cholera!

Whichever medicine you chose, please remember to take it regularly when you are out there and to continue and finish the course once you return home. Bon voyage!!