5 hours if the flight is non-stop and 8 or 9 hours if I would have to change planes. Last year I drove 9 hours from Peoria to Nebraska because flying would have required a connection at ORD. But I flew from Nebraska to Minneapolis because the flight was nonstop and conveniently timed.
Before all the TSA insanity I would have flown much shorter distances, but with all the hassle now it's just not worth it to fly.