I've never been the only one, but close.
November 2001 -- CAE-CVG -- 1 of 2 on a Comair CRJ
Jan 15, 2006 -- ATL-SJD -- On the way to our honeymoon with SkySaver tickets booked in Coach, my wife and I were 2 of 14 on a 767.
Everyone was upgraded to Business class! ^
I wrote about each of these in
Travelbuzz!
http://www.flyertalk.com/forum/trave...-yourself.html