RE: seasickness. Have you tried any of the many otc and prescribed medicines? Check with your health care providers first. The trick is to start the medicine before you board the ship.

To pick a luxury line, you should check out the different lines on CruiseCritic.com, then report back to us! I have sailed on all 3 above-mentioned lines. Alaska is a good choice for a multi-generational family cruise. That narrows it to Regent, and they have great kids programs during the cruise. Seabourn(200) doesn't go to Alaska nor is it for children at all. Cunard is huge(2700 ) and there is a lot to do as well. The smaller ship the better in Alaska, since it can go into different areas. Also check the Alaska BB on Cruise Critic. It's a wealth of information.

I don't think any cruise can promise to be 'totally calm'. You need to be prepared. Cruising is a wonderful holiday.