Originally Posted by PTravel

I'd be careful of registry defraggers. In theory, there is no need to either clean or defrag the registry. I use the Glary Utilities registry cleaner when I've had to manually remove programs because their uninstall features failed -- I don't like having empty or incorrectly-defined keys lying around and the Glary product removes them. A standard file defragger should treat the registry as a file and make sure all segments are contiguous. I think the value in defragging the registry internally, i.e. changing the sequence of keys, is questionable at best.