Thanks everyone, I think my question is answered. All I need to do is set up the intercontinental routings plus whatever intra regional travel I know about, and if my itinerary changes (and it will) just pay the reissue fee.
Thanks for the advice about A/D availability. I know all about that one which is why I'm trying to get at least my intercontinentals booked firm a little way out. I don't mind downgrades to J for short hops...
How long do you think QF will be able to hold out on their A availability for the 380? Clearly they didn't count on the recession when they dreamt up that policy. Personally, I would far rather travel F on a 747 (in A fare bucket) than pay the exorbitant cost of a regular F or R ticket on a 380.