Can't really comment on the load for that route, I'll leave that for someone else.
Keep in mind that if someone books the middle, you could try a -24 hour upgrade to F (for $50 each), but only if there are seats available. But I'm guessing if someone books a middle between two full seats, then the load is going to be high and the F seats would probably be sold out anyway.
(-24 hour upgrades are explained in the
FAQ)